NFL Week 5 Best Bets
Arizona Cardinals at Philadelphia Eagles (-6.5, 45) — 1 p.m. ET
In their seven games starting at 1 p.m. ET over the past two seasons, the Cardinals are 0-7 ATS.
The over is 11-1 in the Cardinals’ past 12 road games.
Buffalo Bills at Cincinnati Bengals (-3, 39.5) — 1 p.m. ET
The Bills are one of two teams to start 4-0 ATS this season (the other is the Kansas City Chiefs), having won outright in two of their three games as an underdog.
The Bills are 11-3 ATS in their past 14 games against the Bengals.
Los Angeles Chargers at New York Giants (-3.5, 45) — 1 p.m. ET
The Chargers are 0-8-1 ATS during their current nine-game losing streak.
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New York Jets at Cleveland Browns (PK, 39.5) — 1 p.m. ET
The total has gone under in seven straight and 11 of the Browns’ past 13 home games.
The Jets are 2-7 ATS in their past nine road games, including an 0-2 record this season.
Jacksonville Jaguars at Pittsburgh Steelers (-8, 42.5) — 1 p.m. ET
The Jaguars are 4-1 ATS with three outright wins as an underdog since Doug Marrone took over as head coach in Week 16 of last season.
San Francisco 49ers at Indianapolis Colts (-1.5, 44.5) — 1 p.m. ET
The Colts are 25-12 ATS against teams with a losing record under Chuck Pagano.
Tennessee Titans (-3, 43.5) at Miami Dolphins — 1 p.m. ET
The Dolphins are 4-1 ATS with four outright wins in their past five games as a home underdog.
The Titans are 6-23 ATS and 8-21 SU in their past 29 games against teams with a losing record.
Carolina Panthers at Detroit Lions (-2.5, 43) — 1 p.m. ET
The Panthers are 2-7-1 ATS in their past 10 regular-season games following a straight up win.
The under is 11-4 in the Lions’ past 15 games.
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Seattle Seahawks at Los Angeles Rams (PK, 46) — 4:05 p.m. ET
The under is 11-3 in the 14 games between these two teams since Pete Carroll took over as the Seahawks’ head coach.
The home team is 9-2 ATS in the past 11 meetings between these teams. This includes a 5-0 ATS mark for the Rams at home during this span.
Baltimore Ravens at Oakland Raiders (-2.5, 39) — 4:05 p.m. ET
The Raiders are 0-6 ATS and 0-6 SU in their past six games without Derek Carr.
Green Bay Packers at Dallas Cowboys (-2, 53) — 4:25 p.m. ET
The Packers have won outright in each of their past three games as an underdog against the Cowboys.
Teams that played on Thursday night are 6-0 ATS in their next game after the extra rest this season (The Packers played the Chicago Bears on Thursday night in Week 4).
The over is 14-3 in the Packers’ past 17 games.
Kansas City Chiefs at Houston Texans (PK, 45.5) — 8:30 p.m. ET
The Chiefs are 8-0 ATS and 8-0 SU in their past eight road games.
Minnesota Vikings (-2.5, 40.5) at Chicago Bears — Monday at 8:30 p.m. ET
The Bears are 12-4 ATS and 14-2 SU in their past 16 home games against the Vikings. This includes a 6-1 ATS mark with six outright wins in their seven games as a home underdog to Minnesota during that span.
Case Keenum is 1-7 ATS with six outright losses in eight career starts when his team is favored.
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